Assessing the Feasibility of Investigating Cardiovascular Risk Factors: A Re-Analysis Using the Framingham Study

Théo Desroches, Félix E. Rivera-Mariani

Research output: Contribution to conferencePoster

Abstract

The Framingham Heart Study is one of the most comprehensive studies of cardiovascular disease (CVD) risk factors. This project evaluates the feasibility of investigating key cardiovascular risk factors using a sample of the data from the Framingham Study, assessing relationships between blood pressure, smoking, gender, and myocardial infarction risk. After familiarizing ourselves with the dataset, we developed research questions to challenge and analyzed sample data (n=11,626) from the Framingham Study. Relationships between systolic (SYSBP) and diastolic (DIABP) blood pressure, smoking, gender-based hypertension predisposition, and myocardial infarction risk were evaluated using correlation and chi-square analyses. A significant correlation was found between SYSBP and CVD (r = 0.2285, p < 0.001), and DIABP and CVD (r = 0.1589, p < 0.001), confirming that higher systolic blood pressure is more strongly linked to CVD. Smokers showed a significantly higher prevalence of CVD (χ² = 5.998, p = 0.0143) compared to non-smokers. Women had a 57.3% prevalence of hypertension, compared to 42.7% in men (χ² = 3.921, p = 0.0477). Hypertension was strongly associated with myocardial infarction (χ² = 90.99, p < 0.001), with over 3,000 hypertensive patients experiencing an MI, compared to fewer than 1,000 non-hypertensive patients. The relationship of lipid profiles, a known risk biomarker for CVD, was not available to be assessed in the dataset. These findings reinforce known CVD risk factors while demonstrating that not all research questions could be fully addressed due to dataset limitations, such as missing lipid profile components.

Original languageAmerican English
StatePublished - Apr 18 2025
EventLynn University 2025 Student Research Symposium - Eugene M. and Christine E. Lynn Library, Boca Raton, United States
Duration: Apr 18 2025Apr 18 2025

Lynn University Events

Lynn University EventsLynn University 2025 Student Research Symposium
Country/TerritoryUnited States
CityBoca Raton
Period4/18/254/18/25

Bibliographical note

Poster Presentation: Health and Social Sciences category

Faculty Sponsor: Dr. Félix E. Rivera-Mariani

Authors' Contributions:
- Mr. Desroches: contributed the original research idea, interpreted the results, and developed the study's conclusions and proposed directions for future research.
- Dr. Rivera-Mariani: Advised on the research concept and design, guided variable selection, deployed data analysis workflow, provided input on results interpretation and future research framing, mentored student through project.

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